目的:探讨生命意义感在家庭经济困难大学生歧视知觉与希望感之间的中介作用,为有效预防家庭经济困难大学生心理危机提供实证依据。方法:采用歧视知觉量表、希望感量表、生命意义感量表对江苏省3所高校的1708名家庭经济困难大学生进行调查。结果:1) 家庭经济困难大学生希望感、生命意义感之间存在显著正相关,二者与歧视知觉均存在显著负相关;2) 歧视知觉对家庭经济困难大学生希望感存在显著的负向影响;3) 歧视知觉还能通过生命意义感的中介作用对家庭经济困难大学生希望感施加间接的负向影响。结论:本研究揭示了歧视知觉与家庭经济困难大学生希望感的关系及其作用机制,发现歧视知觉对家庭经济困难大学生希望感存在负面影响。Objective: To explore the mediating role of the sense of meaning in life between the perception of discrimination and the sense of hope among impoverished college students, and to provide empirical evidence for effectively preventing psychological crises among impoverished college students. The method used the Discrimination Perception Scale, Hope Scale, and Meaning of Life Scale to survey 1708 impoverished college students from three universities in Jiangsu Province. Result: 1) There is a significant positive correlation between the sense of hope and the sense of meaning in life among impoverished college students, and a significant negative correlation between both and the perception of discrimination;2) The perception of discrimination has a significant negative impact on the sense of hope among impoverished college students;3) Perceived discrimination can also have an indirect negative impact on the sense of hope among impoverished college students through the mediating effect of a sense of meaning in life. Conclusion: This study reveals the relationship and mechanism between perceived discrimination and the sense of hope among impoverished college students, and finds tha