背景:口腔疾病患者通常伴有炎症和免疫水平。血小板和淋巴细胞均为常见标志物,与多种疾病的发生和发展有关,且与口腔疾病的进展息息相关。然而,目前还缺乏有关血小板和淋巴细胞比率(PLR)与口腔疾病之间关系的研究。研究方法:本研究纳入了3168名美国成人的统计数据,这些数据来自于2013年至2014年间进行的美国国家健康与营养调查(NHANES)。研究采用了多种定量方法,包括根据收集到的参与者信息制作基线表,同时进行逻辑回归、限制性立方样条分析和分层亚组分析,旨在加强研究结果的可靠性。结果:本次调查涵盖了3168名成年参与者,我们发现PLR与口腔疾病相关。在控制了可能的混杂变量后,发现PLR水平与口腔疾病患病率之间存在显著关联(模型1中Q4 (0.72 (0.57~0.91)),P = 0.016。模型2中Q4 (0.76 (0.62~0.94)),P = 0.039)。RCS曲线证明了这一点(P-非线性 = 0.015)。此外,亚组分析也验证了两者之间的关联。结论:在美国成年人中,口腔疾病的发生与PLR水平的升高呈正相关,这表明PLR可作为评估口腔健康的临床指标。Background: Patients with oral diseases are typically associated with inflammatory processes and alterations in immune function. Both platelets and lymphocytes are commonly used markers that are associated with the development and progression of a variety of diseases and are closely linked to the progression of oral disease. Nevertheless, there is a paucity of research examining the correlation between platelet and lymphocyte ratio (PLR) and oral diseases. Study Methods: The study included statistical data from 3168 U.S. adults from the National Health and Nutrition Examination Survey (NHANES), which was conducted between 2013 and 2014. The study employed a range of quantitative techniques, including the use of a baseline table based on the collected data from the participants, in addition to logistic regression, restricted cubic spline analysis, and str
