目的:测定BPH患者尿道外括约肌运动单位电位(motor unit potential,MUP),统计出相应参数的正常值,为临床上发现“高危”BPH患者尿道外括约肌异常,降低“高危”BPH患者术后尿失禁发生率提供一定依据。方法:采用同心圆针电极经会阴穿刺至尿道外括约肌,用尿动力仪记录肌电信号,测定并记录BPH患者尿道外括约肌MUP。结果:本研究测定BPH患者80例,对每例患者收集符合标准的电位5~10个,记录每个电位的时限和波幅,经统计学分析得出,BPH患者尿道外括约肌MUP的参考值时限为3.46~11.26ms,平均7.36ms,波幅为55~607μV,平均237μV。结论:本研究得出BPH患者的MuP正常值可以用来评估预测相关“高危”BPH患者的尿道外括约肌可能存在的神经肌肉病变,对避免及分析术后尿失禁的原因具有一定的临床运用价值。
Objective: Motor unit potential (MUP) morphology can bequantified using parame ters describing electrophysiological size and shape (complexity). Traditionally, MUP complexity has been estimated using parameters number of phases and turns. Recently, ‘irregularity coefficient’(IR), measuring the length of the MUP curv e normalized with its amplitude, has been introduced. The aim of this study was to evaluate IR in the external anal sphincter muscle. Methods: Sensitivity was e xamined in 61 patients with chronic cauda equina lesions, and specificity in 75 controls using a standard concentric EMG needle and EMG system with multi-MUP a nalysis. Results: When evaluated separately the sensitivity of IR was 16%lower, and specificity 5%higher compared to number of turns, with both differences de creasing to only 2 and 1%, respectively, when each of these parameters was adde d to MUP area and duration.Conclusions: Our present results suggest that IR prov ides a similar diagnostic usefulness, but a more appropriate description of MUP complexity compared to traditional MUP parameters.Significance: IR seems to be s uitable to complement one of MUP parameters measuring electrophysiological MUP s ize in the future quantitative EMG.