A new series of compounds, 2-(benzodioxol-2-yl)acetic acids, have been synthesized. Their structures were confirmed by MS and 1H-NMR. The preliminary pharmacological screening showed that these compounds exhibited potent human PPARδ agonist activities.
Jian Lei KANGZhi Bing ZHENGDan QINLi Li WANGSong LI
The synthesis of a series of 3,6-dichloropyridazine derivatives was described.In vitro experiment,all compounds exhibited ananti-rhinovirus activity,and one of the compounds 6g showed the comparable activity as our lead compound pirodavir.
Shi Yong FanChun Lai MiJun YangSong LiZhi Bing Zheng
