[ Objective] The aim was to study the natural environment of Karst mountain areas in northern Guangdong. [ Method] Through the col- lection of topography, climate, soil and vegetation data in the Karst mountain areas of Northern Guangdong, combined with field investigation, the natural environment of Karst mountain areas in northern Guangdong was analyzed. [ Result] The Karst topography of the area is widely distributed. Most places were in subtropical climate zone, with high temperature and rainfall in the same period, and abundant precipitation. There was a large area of contiguous distribution of limestone with dissolution area. Vegetations included typical limestone evergreen and deciduous broadleaved mixed forest, limestone shrub and grassy slopes in mountain and hill. Limestone vegetation had typical limestone mixed evergreen broadleaf forest, limestone shrub, limestone hilly mountain grass slope. [ Conclusion] The study provided theoretical basis for the protection of natural environment of Karst mountain areas in northern Guangdong.