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国家自然科学基金(30725034)

作品数:2 被引量:10H指数:2
相关作者:刘刚赵明辉喻小娟更多>>
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补体旁路途径调节异常在C3肾小球病中的研究进展被引量:6
2011年
目前研究发现补体调节异常与多种原发性肾小球疾病相关,证据较为充分的包括致密物沉积病(DDD)和C3肾小球肾炎(C3 glomemlonephritis)。DDD的特征性改变为电镜下肾小球基底膜(GBM)致密层见均质飘带状电子致密物沉积,免疫荧光只有c3沉积,免疫球蛋白阴性或很少量沉积。C3肾小球肾炎肾脏病理表现为免疫荧光下只有c3沉积,免疫球蛋白阴性,电镜在系膜区或伴有内皮下有电子致密物沉积,GBM内无电子致密物。
喻小娟刘刚赵明辉
关键词:肾小球病C3旁路途径补体致密物沉积病原发性肾小球疾病
Evaluation of renal artery stenosis using color Doppler sonography in young patients with multiple renal arteries被引量:4
2011年
Background Some individuals have multiple renal arteries. Severe stenosis in one of the arteries may cause refractory hypertension. The detection of stenosis within one of the multiple renal arteries usually required invasive procedures, such as computed tomographic angiography (CTA) and magnetic resonance angiography (MRA). This study reported the application of color Doppler sonography (CDS) in the detection of severe stenosis in one of the multiple arteries. Methods Patients with multiple renal arteries and one of the arteries with severe stenosis were retrospectively studied. Peak systolic velocities (PSV) of renal arteries and the intrarenal CDS patterns were collected and compared. The diagnosis was confirmed by digital subtraction angiography (DSA). Results Four children with multiple renal arteries and one of the arteries with stenosis were investigated. They were admitted due to refractory hypertension. CDS screening identified two renal arteries in one kidney of each patient with one of the two renal arteries having stenosis 〉70%. The PSV of the stenosed arteries were much higher, and the intrarenal CDS patterns supplied by the stenosed arteries changed into T-P patterns. Conclusion Non-invasive CDS technology may be a useful method to identify severe stenosis in one of multiple renal arteries in younq patients.
QIN WeiZHANG XinYANG MinZHONG Xu-huiZHAO Ming-hui
关键词:ANGIOGRAPHY
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