[Objective] This study aimed to analyze the potential geography distribution of M.tanajoa in Yunnan.[Method] The suitability of M.tanajoa in Yunnan was studied in this paper using Maxent and ArcGIS,based on the biological data and known distribution of M.tanajoa,and meteorological data from years of 1950-2000 in WorldClim.[Result] The results showed that there were four levels of suitability assessment of M.tanajoa in Yunnan,in which western and eastern areas are in the most suitability,including part areas of Simao,Lincang,Baoshan,Nujiang,Diqing,Qujing and Wenshan areas.[Conclusion] The potential geographic distribution of M.tanajoa in Yunnan defined in this paper constructed the theory basis and technical support for scientifically forming of quarantine policy and measure for M.tanajoa in China.