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河北新华科极兽药有限公司

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48 条 记 录,以下是 1-10
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中药对猪生长性能和僵猪活化的影响被引量:2
2012年
腹泻是一种多因素引发的疾病,常会导致饲料报酬率低、成活率下降、生长缓慢、生长发育停滞(僵猪),甚至死亡。1月龄-3月龄的猪多发,有的规模猪场仔猪腹泻发病率高达50%以上,死亡率15%-20%,是引起生长受阻和高死亡率的重要原因,每年给养猪业带来直接经济损失上亿元。
高光平高桂生张东林张艳英史秋梅梁银聚邵欣华
关键词:僵猪活化中药直接经济损失仔猪腹泻饲料报酬
犬瘟热病毒单克隆抗体的制备和鉴定被引量:1
2013年
将从水貂中分离的犬瘟热病毒(CDV)HB株,以培养纯化的犬瘟热病毒HB株免疫BALB/c小鼠,采用B淋巴细胞杂交瘤技术,通过ELISA筛选,获得3株能稳定分泌抗犬瘟热病毒结构蛋白的单克隆抗体杂交瘤细胞株。3株单克隆抗体菌属于IgG1亚类,其腹水效价可达到1∶51 200和1∶204 800,细胞培养上清液效价可达到1∶256和1∶512。ELISA分析表明,单抗仅与CDV发生特异性反应,而与犬细小病毒(CPV)和犬腺毒(CAV)没有交叉反应;荧光免疫染色检测进一步表明单克隆抗体的特异性好。该特异性单抗的制备为建立有效检测犬瘟热病毒感染的方法奠定基础。
史秋梅潘素敏贺英张艳英邵新华李彩虹
关键词:犬瘟热病毒单克隆抗体
Breeding Soundness Examination of Breeding Bull after Infecting Mycoplasma wenyonii
2013年
[Objective] The research aimed to study the reproductive health of breed- ing bull after infecting Mycoplasma wenyoniL [Method] The blood and semen quality of breeding bull before and after drug treatment was studied by the methods of blood routine examination and breeding soundness examination (BSE). [Result] Be- fore the treatment with primaquine phosphate, slight anaemia was seen in diseased bull and a lot of M.wenyonfi were seen on blood smears. The scrotal wall of dis- eased bull swelled, testis was softened, the semen quality was reduced, semen quality was decreased and the proportion of primary and secondary deformed sperms was increased. After drug treatment, M.wenyonfi quickly disappeared from blood and the clinical systems were gradually alleviated, so BSE of breeding bulls after one month was passed. [Conclusion] The research laid the foundation for fur- ther study on the relationship between M.wenyonfi and the reduction of bull's repro- ductive functions.
李正本高光平高桂生史秋梅张艳英邵新华梁银聚
利用现代中药技术防治禽细菌性传染病的研究与开发
史秋梅高桂生张艳英高光平张孟杰邵欣华李彩虹王凤霞张彤马文军葛素文等
课题研究对河北省及周边地区1983-2013年间规模化养鸡场大肠杆菌病的发生情况进行了系统流行病学调查。分离鉴定了90株大肠杆菌,分属21个血清型,其中○38和○78为优势血清型。对优势血清型○38分离株的病原生物学进行...
关键词:
关键词:细菌性传染病中药防治流行病学调查
固体光气合成硝唑尼特的工艺研究被引量:4
2012年
采用固体光气代替传统的腐蚀性强、污染大的二氯亚砜作为酰氯化试剂,以乙酰水杨酸为起始原料,在无水环己酮溶剂中经酰氯化、酰胺化合成硝唑尼特。通过单因素试验和正交试验考察了原料配比、反应温度、反应时间以及催化剂种类等因素对反应的影响。结果表明:主要因素的影响程度为乙酰水杨酸与固体光气的摩尔比>催化剂种类>酰氯化反应温度>酰氯化反应时间。较佳的工艺条件为乙酰水杨酸与固体光气的摩尔比为1∶0.40,乙酰水杨酸与2-氨基-5硝基噻唑摩尔比为1∶1.1,以三乙胺作催化剂与缚酸剂,酰氯化反应温度为60℃,酰氯化反应时间为8 h,收率可达80.6%(以乙酰水杨酸计)。
赵地顺王薇唐二军付江涛郑连义梁策
关键词:固体光气乙酰水杨酸
清热解暑散对热应激奶牛血液HSP70及其相关激素和酶的影响
随着人们生活水平不断提高、消费习惯改变以及饮食结构的变化,牛奶的需求量越来越大。早在2005年,全国人均牛奶占有量就已从原来的6.8kg,提高到9kg。专家预测,2015年到2030年期间奶牛的发展速度将会更快。要提高牛...
王海艳杨倩焦玉兰邵欣华梁银聚史万玉
关键词:奶牛血清热应激蛋白HSP70清热解暑相关激素
Antibacterial Activity of Herbal Preparations against Staphylococcus aureus and Streptococcus agalactiae in Cow Mastitis
2013年
[Objective] This study aimed to analyze the antibacterial activity of herbal preparations against Staphylococcus aureus and Streptococcus agalactiae in cow mastitis. [Method] The crude drug solutions of four different prescriptions for Zengrujianniusan were prepared through reflux extraction. Their antibacterial activity in vitro against Staphylococcus aureus and Streptococcus agalactiae in cow mastitis were investigated. [Result] All the four different prescriptions exhibited antibacterial activity against S. aureus and S. agalactiae. Among them, prescription Ⅲ was extremely sensitive, and had the best bactericidal effect. The other three prescriptions were highly sensitive. [Conclusion] This study provides a theoretical basis for the development of herbal preparations for the treatment of cow mastitis.
高桂生高光平李正本史秋梅张艳英邵新华梁银聚
中药对脾虚仔猪胃蛋白酶和胰蛋白酶的影响被引量:1
2012年
[目的]确定自拟的固肠促长散对脾虚仔猪胃蛋白酶和胰蛋白酶的影响。[方法]采用给仔猪注射利血平和交替不喂与喂饱的方法构建脾虚仔猪模型,分别在注射利血平前、最后一次注射利血平当天、灌药结束后次日及第8天测定仔猪的胃蛋白酶活力和胰蛋白酶含量。[结果]试验结束后,固肠促长散组的各种酶活性与正常对照组差异不显著,脾虚对照组和思密达组的各种酶活性与正常对照组差异显著。[结论]固肠促长散能促进利血平所致脾虚仔猪的胃蛋白酶活力和胰蛋白酶恢复。
高光平高桂生张东林张艳英史秋梅梁银聚邵欣华
关键词:胃蛋白酶胰蛋白酶中药
Histological Effects of Guchangcuzhang Powder on Parenchymatous Organs in Experimental Piglets with Spleen Weakness
2013年
[Objective] This study aimed to explore the histological effects of Guchangcuzhang powder on the parenchymatous organs in experiment piglets with spleen weakness. [Method] For the 12 healthy piglets, 0.5 ml of reserpine was injected at their jugular muscle once every day for 10 days. Afterwards, the 12 piglets with diarrhea were divided into two groups, namely the Guchangcuzhang powder group and the control group, six in each. In the former group, 6 g of Guchangcuzhang powder was brewed with 20 ml of boiling water and then the piglets were drenched with the medication solution for 7 d once every day; in the latter group, each piglet was drenched with 20 ml of normal saline once every day for 7 d. On two and eight days after the drug discontinuance respectively, three piglets were selected from each of the group and killed by bloodletting from the jugular vein. Afterwards, paraffin sections of heart, liver, lungs and kidney was made and then stained respectively, followed by observation of the histological changes.[Result] The histological structure of each parenchymatous organ in piglets drenched with Guchangcuzhang powder restored or approached to normal. [Conlusion]Guchangcuzhang powder has a good therapeutic against diarrhea in piglets.
沈萍张艳英高桂生史秋梅高光平邵欣华
关键词:PIGLETSDIARRHEA
治疗奶牛乳房炎的中草药饲料添加剂
本发明涉及一种治疗奶牛乳房炎的中草药饲料添加剂,它是由下列重量配比的原料制成的药剂:蒲公英5-7份,穿心莲4-6份,鱼腥草2-4份,连翘2-4份,金银花2-4份,野菊花2-4份,黄连1-2份,黄芩2-3份,甘草1-2份。...
史秋梅高桂生高光平张艳英沈萍邵欣华梁银聚
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