Many cembranes, 14 membered ring diterpenoids, were reported to have antitumor and antimicrobial activities. Soft corals are rich sources of cembrenoid diterpenes. We reported cembrenoids lactones, such as sarcophinone, iso sarcophinone, sarcophine, sartrochine from the species of Sarcophyton in our earlier papers,. In continuation of our studies on the soft coral Sarcophyton , we obtained a new cembranoid lactone, named sarcophydiol(1) from a specimen of Sarcophyton sp . collected around the bay of Sanya, Hainan Island. On the basis of spectroscopic methods, its structure was determined as ( 10S *,11S *) 3,7,11α ,15 tetramethyl 10 β,11β dihydroxy cembr 2 E,6E,14(15)Z trien 16,1 olide(1). The bioactivities of compound 1 were under investigating.
Two new steroidal glycosides and one polyhydroxylated sterol were isolated from the soft coral Cladiella sp. by HPLC fractionation. The animal material was collected from Sanya bay, Hainan province, China. On the basis of spectroscopic analysis and chemical conversion, their chemical structures were elucidated as pregn-5,20-dien-3β-ol-3-O-α-L-fucopyranoside(1), pregn-5,20-dien-3β-ol-3-O-β-D-xylopyranoside(2) and (22E,24R)-ergost-7,22-dien-3β,5α,6β-triol(3). Compounds 1 and 2 are new compounds.
