In order to investigate the mechanisms of anti-inflammation and immunity of moxibustion, experiments in animals were made. The results showed the effects of moxibustion were as follows: (1) inhibiting edema and exudation in acute inflamrnation, (2)preventing and treating proliferation of granulomain subacute inflammation, (3)resisting inflammation and decreasing swelling in chronic inflammation,(4)protecting n1urine thymus and spleen in decllning immune function, (5 ) promoting proliferative responses of splenocytes in adjuvant arthritic (AA) rats, (6 ) possessing the effect of dual-directional regulation on cell factors which induce AA rats to be immune disorder. This study indicates that moxibustion has remarkable anti-inflammatory and immunoregulative effects. It may be and important aspect ofmechanism to prevent and treat