目的:探讨细菌性腹膜透析导管相关感染合并慢性肉芽肿的经验性治疗。方法:通过对1例细菌性腹膜透析导管相关感染合并慢性肉芽肿的病历回顾性分析,对腹膜透析导管相关感染与腹膜透析相关性腹膜炎的相关性以及腹膜透析隧道感染超声检查的必要性。结果:通过静脉应用抗生素、局部换药室换药、齿镊搔刮肉芽组织、局部浸润麻醉拔除原导管,对侧经皮穿刺腹膜透析置管术后,患者腹膜透析导管相关感染合并慢性肉芽肿得到有效的控制,病情好转出院。Objective: To explore the empirical treatment of bacterial peritoneal dialysis catheter-related infection with chronic granuloma. Methods: A retrospective analysis was conducted on the case of bacterial peritoneal dialysis catheter-related infection with chronic granuloma to investigate the correlation between peritoneal dialysis catheter-related infection and peritoneal dialysis-related peritonitis, and the necessity of ultrasound examination for peritoneal dialysis tunnel infection. Results: The patient’s peritoneal dialysis catheter-related infection with chronic granuloma was effectively controlled and the condition improved after the treatment of intravenous antibiotics, local dressing changes, tooth forceps excision of granulomatous tissue, and local infiltration anesthesia for catheter removal from the contralateral percutaneous peritoneal dialysis placement.