The stability constants of inclusion complexes of some benzene derivations with β cyclodextrin (β CD) in aqueous solution were studied by ultraviolet spectrophotometry at 20℃,30℃,40℃ and 50℃,respectively.The apparent thermodynamic parameters were also obtained.The results demonstrated that van der Waals force (Δ H <0,Δ S <0,governed by Δ H ) is the major driving force of inclusion systems of benzene derivations with β CD.On the other hand,in the case of inclusion complex of vanillin,the hydrogen bonding may also play a role in complexation.
The thermal decomposition kinetics of three inclusion complexes of βcyclodextrin with cholesterol,sebacic acid,and vanillin was studied by using non-isothermal thermogravimetry.Their average apparent activation energies of the thermal decomposition were obtained.The experimental result indicated that several weak interactions cooperatively contributed to the inclusion complexation of the βcyclodextrin hosts,and the complex thermal stability were dominated by the size/shape-matching between host and guest and hydrogen band interaction,however,the quantitative ratio do not obviously iv the complex thermal stability.
