Membranous nephropathy （MN） is the most common cause of nephrotic syndrome in adults.The renal biopsy is the gold standard for the disease diagnosis,but is invasive.M-type phospholipase A2 receptor （PLA2R） on human podocytes could serve as the target for podocytopathic antibodies （anti-PLA2R）.1 Patients with iMN （70%-80%） were found the circulating antibodies against PLA2R.1 And the podocyte-secreted angiopoietinlike-4 （Angptl4） could be another key role in nephrotic syndrome3.
CHEN Wen-qing ZHANG Ying JIANG Hong LI Heng LI Xia-yu YANG Xian FENG Shi WANG Yu-chen LIN Chuan SHEN Xiu-jing ZHOU Qin JIN Juan CHEN Jiang-hua
