Fifteen compounds were isolated from the processed seeds of Strychnos nux-vomica and were identified as follows:strychnine(1),brucine(2),pseudostrychnine(3),pseudobrucine(4),secoxyloganin(5),caffeic acid(6),p-hydroxybenzoic acid(7),p-hydroxyphenylacetic acid(8),uvaol(9),stigmasta-7,22,25-triene-3-ol(10),lupeol(11),11-oxo-α-amyrin palmitate(12),catechol(13),maltol(14),adenosine(15).Compounds 5-15 were isolated from genus Strychnos for the first time.